Ing. Miguel Ángel Gallardo Ortiz,
WWW.CITA.ES
Tel: (+34) 914743809 Fax: 902998379 Móvil (GSM): (+34) 619776475,
Apartado (P.O. Box) 17083, E-28080 Madrid, Spain, E-mail:
miguel@cita.es
This is a list (1994-2003) of European references on Cancer/Radioactivity
research.
At the end of this list you can find information about Topics for the Call
2004 on Radioprotection
and indicative topics for future calls
We are interested in any further information, statistical data, methodologies
and contacts.for proposals.
Please visit http://www.cita.es/mcr
and send a message to miguel@cita.es
Record Control Number: 14138
Quality Validation Date: 1994-01-23
Update Date: 2003-02-28
Title: HEALTH EFFECTS OF CHRONIC EXPOSURE
TO LOW DOSE IONIZING RADIATION ON WORKERS OF THE SPANISH NUCLEAR ENERGY
INSTITUTE
Subject Index : Radiation Protection
Other Indexes: DATA BASES; EPIDEMIOLOGY; HEALTH SURVEYS; IONIZING RADIATION;
RADIATION EFFECTS
; RADIATION PROTECTION
Objective: The objectives are to compare the mortality of JEN workers with
the national rates, and if there were any evidence suggesting that the mortality
at JEN is greater than that in Spain, to establish whether this difference
is related to radiation exposure.
General Information: The study design corresponds to a retrospective cohort
study on 5303 JEN workers from 1954 to 1986. This cohort constitutes 85%
of the JEN labour force. Data collection for each worker comprises:
administrative and clinical data;
exposure information (dosimetry); and
cause specific mortality data.
The statistical analysis has been carried out in two steps:
external comparison of the JEN mortality with the mortality of the Spanish
population, through standardized mortality ratios;
internal comparison of the cohort mortality by radiation exposure, through
log-linear models.
So far the results suggested that the mortality among JEN workers is generally
lower than the national rates (healthy worker effect). However, a significant
increase in the cancer mortality among the study cohort has been observed.
This increase has not shown a radiation dose-effect relationship.
Achievements: A retrospective study was conducted on a cohort of 5303
Spanish Nuclear Council
(JEN) workers. Information was obtained from the JEN dosimetry service
records. Standardized mortality ratios (SMR) for the principal causes of
death for the period 1954 to 1986 were used to compare the mortality of the
JEN cohort with the mortality of the Spanish population. The results suggest
that the mortablity among JEN workers is generally lower than the national
rates due to the healthy worker effect. However, a significant increase in
the mortality from cancer among the study cohort was observed. This increase
has not shown a radiation dose effect relationship.
A program of epidemiological surveillance to identify cases of illness,
injury and/or exposure to risk factors present in JEN, is being carried out.
The secondary collection of information from existing data sources such as:
mortality statisics;
national statistics of work injuries and occupational illnesses;
worer compensation files;
hospital discharge records;
the population based cancer registry
is under way. A structural standard questionnaire to be used as part of
periodic medical examinations of JEN workers is being developed and tested.
A detailed assessment of the radiation exposure of all workers since 1954
has been conducted and a program of surveillance of other hazards specific
to JEN is being prepared.
Start Date: 1987-07-01
End Date: 1992-03-31
Duration: 57 months
Project Status: Completed
Programme Type: 1st FWP (First Framework Programme)
Programme Acronym : RADPROT 6C
Subprogramme Area: RISKS AND MANAGEMENT
OF RADIATION PROTECTION
ASSESSMENT OF HUMAN EXPOSURE AND RISKS
Project Reference: BI6*0229
Contract Type: CSC (Cost-sharing contracts)
Prime Contractor
Organisation: CENTRO DE INVESTIGACIONES ENERGETICAS MEDIOAMBIENTALES Y
TEC NOLOGICAS
Address: MEDIOAMB.Y TECNOLOG.(CIEMAT) AVDA COMPLUTENSE, 22
City: 28040
Country: SPAIN
Contact Person: Name: DAVIES
Record Control Number: 52738
Quality Validation Date: 2003-04-01
Update Date: 2003-05-05
Project Acronym: RADNA
Title: Induction, repair and biological consequences of DNA damages caused
by radiations of various qualities
Subject Index : Nuclear Fission; Medicine, Health; Radiation Protection;
Safety
Objective: Evaluation of radiation risk at the low dose rates that generally
apply in occupational, environmental and medical diagnostic exposures requires
extrapolation of the risks know from high-dose acute exposures, mainly from
follow-up of A-bomb survivors. The proposal aims to provide data, which
will improve understanding of dose-versus-risk relationships to input into
mechanistic models of radiation carcinogenesis for these extrapolations.
We propose to obtain data on cellular mechanisms of radiation effects which
are believed to lead to cancer: DNA damage and its cellular processing into
stable genomic damage as chromosomal aberrations and mutations. A novel
feature is to use counted charged particle micro-beam techniques to mimic,
using cells in vitro, the single-particle effects that dominate protection-level
exposures. The studies include low-dose effects that dominate protection-level
exposures. The studies include low-dose effects of radiation quality (LET)
which relate to radiation weighting factors.
Start Date: 2000-02-01
End Date: 2003-07-31
Duration: 42 months
Project Status: Execution
Project Cost: 1.28 million euro
Project Funding: 1.08 million euro
Programme Type: EAEC FWP (Euratom Framework Programme)
Programme Acronym : FP5-EAECTP C
Subprogramme Area: Radiation protection and health - Risk estimates for
exposures at low dose and low dose rate
Project Reference: FIGH-CT-1999-00012
Contract Type: CSC (Cost-sharing contracts)
Prime Contractor
Organisation: GRAY LABORATORY CANCER RESEARCH TRUST
Organisation Type: Research
Department: Gray Laboratory
Address: Mount Vernon Hospital
PO Box 100
Postcode: HA6 2JR
City: NORTHWOOD
Region: SOUTH EAST (UK)
GREATER LONDON
Country: UNITED KINGDOM
Contact Person: Name: EVERS, Jane (Dr)
Tel: +44-1923-828611
Fax: +44-1923-835210
Email: evers@graylab.ac.uk
Other Contractors
Organisation Name: ISTITUTO NAZIONALE DI FISICA NUCLEARE
Organisation Type: Research
Contact Person: IAROCCI, Enzo (Professor)
Department: LABORATORI NAZIONALI DI LEGNARO
Address: Via Romea 4
City: LEGNARO
Region: NORD EST
VENETO
Padova
Org. Country: ITALY
Postcode: 35020
Telephone: +39-066-840031
Fax: +39-066-8307924
E-mail: segreteria@presid.infn.it
Organisation Name: SAARLAND UNIVERSITY
Organisation Type: Education
Contact Person: HÖNN, Guenther (Professor)
Department: FACHRICHTUNG BIOPHYSIK UND PHYSIKALISCHE GRUNDLAGEN DER MEDIZIN
Address: Klinikium Bau 76
City: SAARBRUECKEN
Region: SAARLAND
Stadtverband Saarbrücken
Org. Country: GERMANY
Postcode: 66041
Telephone: +49-681-3024801
Fax: +49-681-3024142
E-mail: eu-referent@univw.sb.de
Organisation Name: ISTITUTO SUPERIORE DI SANITA
Organisation Type: Research
Contact Person: BENAGIANO, Giuseppe (Professor)
Department: LABORATORIO DI FISICA
Address: Viale Regina Elena 299
City: ROMA
Region: LAZIO
Roma
Org. Country: ITALY
Postcode: 00161
Telephone: +39-064-9902
Fax: +39-064-4869440
E-mail: diriss@iss.it
Organisation Name: LEIDEN UNIVERSITY
Organisation Type: Education
Contact Person: VAN GREVENSTEIN, Paul (Mr)
Department: DEPARTMENT OF RADIATION GENETICS AND CHEMICAL MUTAGENESIS PRE-CLINICAL
LABORATORIES
Address: Wassenaarseweg 72
P.B. 9503
City: LEIDEN
Region: WEST-NEDERLAND
ZUID-HOLLAND
Agglomeratie Leiden en Bollenstreek
Org. Country: NETHERLANDS
Postcode: 2300 RA
Telephone: +31-7-15276010
Fax: +31-71-5276321
E-mail: p.v.u.van_grevenstein@pkl.medfac.leidenu
Organisation Name: UPPSALA UNIVERSITY
Organisation Type: Education
Contact Person: OTTOSSON, Mats Ola (Dr)
Department: DEPARTMENT OF ONCOLOGY, RADIOLOGY AND CLINICAL IMMUNOLOGY
Address: Dag Hammarskjölds väg 20
P.O. Box 256
City: UPPSALA
Region: ÖSTRA MELLANSVERIGE
Uppsala län
Org. Country: SWEDEN
Postcode: 751 85
Telephone: +46-18-4713312
Fax: +46-18-4711640
E-mail: mats_ola.ottosson@uadm.uu.se
Organisation Name: KFKI - ATOMIC ENERGY RESEARCH INSTITUTE - HUNGARIAN
ACADEMY OF SCIENCES
Organisation Type: Research
Contact Person: GADÓ, János (Dr)
Department: RADIATION AND ENVIRONMENTAL PHYSICS DEPARTMENT
Address: Konkoly-Thege ut 29-33
P.O. Box 49
City: BUDAPEST
Region: MAGYARORSZAG
Org. Country: HUNGARY
Postcode: 1121
Organisation Name: STOCKHOLM UNIVERSITET
Organisation Type: Education
Contact Person: LINDENCRONA, Gustaf (Professor)
Department: DEPARTMENT OF MOLECULAR GENOME RESEARCH
Address: Stockholm University
City: Stockholm
Region: STOCKHOLM
Org. Country: SWEDEN
Postcode: 106 91
Telephone: +46-81-62271
Fax: +46-81-61938
E-mail: rektor@adm.su.se
Organisation Name: JUSTUS-LIEBIG-UNIVERSITY OF GIESSEN
Organisation Type: Education
Contact Person: HORMUTH, Stefan (Professor)
Department: STRAHLENZENTRUM, FACHBEREICH PHYSIK
Address: Leihgesterner Weg 217
City: Giessen
Region: HESSEN
GIEßEN
Gießen, Landkreis
Org. Country: GERMANY
Postcode: 35392
Telephone: +49-641-9912000
Fax: +49-641-9912009
E-mail: hortmuth@admin.uni.giessen.de
Organisation Name: NATIONAL CENTRE FOR SCIENTIFIC RESEARCH 'DEMOKRITOS'
Organisation Type: Research
Contact Person: ITHAKISSIOS, Dionyssios (Professor)
Department: INSTITUTE OF BIOLOGY
Address: Patriarchou Grogoriou
P.O.Box 60228
City: ATHENS
Region: ATTIKI
Org. Country: GREECE
Postcode: 15310
Telephone: +30-210-6513021
Fax: +30-210-6510594
E-mail: graf.proedrou@gel.demokritos.gr
Organisation Name: GEORG-AUGUST-UNIVERSITY GOETTINGEN
Organisation Type: Education
Contact Person: FROST, Marina (Dr)
Department: ABTEILUNG KLINISCHE STRAHLENBIOLOGIE UND KLINISCHE STRAHLENPHYSIK
Address: Von-Siebold-Straße 3
City: Göttingen
Region: NIEDERSACHSEN
BRAUNSCHWEIG
Göttingen
Org. Country: GERMANY
Postcode: 37075
Telephone: +49-551-394202
Record Control Number: 26083
Quality Validation Date: 1995-04-20
Update Date: 2003-03-04
Title: Estimates of cancer risks of exposure to radon based on epidemiological
studies in czechoslovak miners and follow-up of mortality in monitored radiation-exposed
workers and uranium miners in hungary
Subject Index : Coordination, Cooperation; Scientific Research
Start Date: 1993-08-01
End Date: 1994-12-31
Duration: 17 months
Project Status: Completed
Programme Type: IC (International Cooperation)
Programme Acronym : PECO/COPERNICUS
Subprogramme Area: CEEC participation in NUCLEAR FISSION SAFETY programme
(RADIATION PROTECTION) - CEEC participation in NUCLEAR FISSION SAFETY programme
(RADIATION PROTECTION)
Project Reference: CIPD925029
Contract Type: CSC (Cost-sharing contracts)
Prime Contractor
Organisation: GSF-RESEARCH CENTER FOR ENVIRONMENT AND HEALTH
Organisation Type: Research
Department: INSTITUT FUER STRAHLENSCHUTZ
Address: Ingolstaedter Landstrasse 1
Postfach 11 29
Postcode: 85764
City: OBERSCHLEISSHEIM
Region: BAYERN
OBERBAYERN
München, Landkreis
Country: GERMANY
Contact Person: Name: CHMELEVSKY, D (Dr)
Other Contractors
Organisation Name: National Institute of Public Health
Organisation Type: Non Commercial
Contact Person: KUNZ, Emil
Department: Centre of Radiation Hygiene
Address: 48 Srobárova
City: Praha 10
Region: CESKA REPUBLIKA
Org. Country: CZECH REPUBLIC
Postcode: 100 42
Organisation Name: "FREDERIC JOLIOT CURIE" NATIONAL RESEARCH INSTITUTE
FOR RADIOBIOLOGY AND RADIOHYGIENE - NATIONAL CENTER OF PUBLIC HEALTH
Organisation Type: Research
Contact Person: TURAI, Istvan
Address: 5 Anna u. 5
P.O. Box 101
City: BUDAPEST
Region: MAGYARORSZAG
Org. Country: HUNGARY
Postcode: 1775
Record Control Number: 35557
Quality Validation Date: 2001-12-07
Update Date: 2003-03-04
Title: Risk assessment of radiation induced thyroid cancer in children
andyoung adults exposed due to the Chernobyl accident
Subject Index : Biotechnology; Coordination, Cooperation; Legislation,
Regulations; Life Sciences; Medicine, Health; Policies; Radiation Protection;
Social Aspects
Other Indexes: Chernobyl; thyroid; dose reconstruction; risk; children;
131I
General Information: The Chernobyl accident gives an unique possibility
to investigate radiation-induced thyroid cancer risk as a function of age
at exposure, sex, dose and time since irradiation. Hundreds of thousands of
people in Belarus, Ukraine and Russia were exposed after the accident. Particularly,
131I caused very high doses absorbed in the thyroid due to its concentration
in this gland. In some areas, the individual doses estimated on the basis
of 131I activity measurements in the thyroids have reached 10-15 Gy for children
and about 1-1.5 Gy for adults. All ages, males and females are present in
the exposed and measured populations.
The present dose estimations are mainly based on about 267000 measurements
of the 131I activity in the thyroid. In the proposed research results of
131I concentration in milk, greens, foodstuffs and soil will be used as well.
In territories where no radioiodine measurements were performed, doses will
be assessed on the basis of correlation with 137Cs deposition on soil and
with dose rates in air in May-June 1986. Additionally, questionnaire data
will be used. The possibilities to use the results of atmospheric dispersion
modeling and measurements of 129I concentration in soil will be investigated.
In 1986-1994, 1024 thyroids cancers have been reported in children and
young adults who were in the age of 0 to 18 years at the time of the accident.
Already now, 10 years after the accident, we have the opportunity to develop
and analyze the biggest thyroid cancer register for children. Since 1990,
in Ukraine and Belarus, the increase in thyroid cancer in exposed populations
greatly exceeded the increase of baseline rate. In 1990-1994 in some areas,
this increase was up to 100-fold for children aged 0-8 years at the time
of the accident. A preliminary analysis has shown that the thyroid cancer
incidence increased with the dose received.
The main ail of the proposed research is to estimate the radiation thyroid
cancer risk for the children. To attain this aim, dosimetric models will
be developed and thyroid doses will be estimated for different populations;
thyroid cancer incidence in children will be assessed and analyzed; statistical
methods in risk assessment will be adapted to the limitations and uncertainties
of available data, radiation risk functions will be estimated for the time
of observation; predictions for future rates in the contaminated areas will
be given.
Achievements: Foreseen Results
The risk assessment of late effects of thyroid exposures is a fundamental
issue of human radiobiology. Simultaneously, the thyroid dose estimates
will be applied to the health monitoring of exposed populations after the
Chernobyl accident.
Reported thyroid cancer incidence and thyroid dose assessments in the areas
of the former Soviet Union contaminated after this accident will be available
for the international scientific analysis. Experience achieved in this study
and obtained results should be used in strategy of nuclear energy development,
designing of radiation protection standards and in the countermeasure planning.
Start Date: 1997-02-01
End Date: 1999-04-30
Duration: 27 months
Project Status: Completed
Project Funding: 215000.00 ECU
Programme Type: 4th FWP (Fourth Framework Programme)
Programme Acronym : INCO
Subprogramme Area: Health - Health consequences of radiation exposure
Project Reference: IC15960306
Contract Type: CSC (Cost-sharing contracts)
Prime Contractor
Organisation: GSF-RESEARCH CENTER FOR ENVIRONMENT AND HEALTH
Organisation Type: Research
Department: INSTITUT FUER STRAHLENSCHUTZ
Address: Ingolstaedter Landstrasse 1
Postfach 11 29
Postcode: 85764
City: OBERSCHLEISSHEIM
Region: BAYERN
OBERBAYERN
München, Landkreis
Country: GERMANY
Contact Person: Name: GOULKO, Guennadi
Tel: +49-893-1872225
Fax: +49-893-1873363
Email: goulko@gsf.de
Other Contractors
Organisation Name: Imperial Cancer Research Fund
Organisation Type: Research
Contact Person: BERAL, Valerie
Department: Cancer Epidemiology Unit
Address: The Radcliffe Infirmary, Gibson Building
City: Oxford
Region: SOUTH EAST (UK)
BERKSHIRE, BUCKINGHAMSHIRE, OXFORDSHIRE
Oxfordshire
Org. Country: UNITED KINGDOM
Postcode: OX2 6HE
Telephone: +44-1865-311933
Fax: +44-1865-310545
E-mail: gkreeves@vax.ox.ac.uk
Organisation Name: Institute of Radiation Hygiene
Organisation Type: Research
Contact Person: BALONOV, Michael
Department: Research and Technical Centre "Protection"
Address: 20/81 Leninstreet
City: St. Petersburg
Org. Country: RUSSIAN FEDERATION
Postcode: 197136
Telephone: +7-81-22334843
Fax: +7-81-22495309
E-mail: ira@protection.spb.su
Organisation Name: Ukrainian Radiation Protection Institute
Organisation Type: Research
Contact Person: SOBOLEV, Boris
Department: Department of Risks and Applied Analysis
Address: 53 Melnikov Street
City: Kiev
Org. Country: UKRAINE
Postcode: 254050
Telephone: +380-44-2137182
Fax: +380-44-2137192
E-mail: vil@rpi.kiev.ua
Organisation Name: Scientific Centre for Oncological Pathology of the Thyroid
Gland
Organisation Type: Research
Contact Person: KENIGSBERG, Jacov
Department: Institute of Radiation Medicine
Address: 23 Masherov Avenue
City: Minsk
Org. Country: BELARUS
Postcode: 220600
Telephone: +375-1-72269480
Fax: +375-1-72321344
Record Control Number: 51891
Quality Validation Date: 2001-12-07
Update Date: 2003-03-05
Title: Cancer risks among individuals exposed to ionizing radiation in
the New Independent States focusing on methodological considerations and
development
Subject Index : Biotechnology; Coordination, Cooperation; Legislation,
Regulations; Life Sciences; Medicine, Health; Policies; Radiation Protection;
Social Aspects
Other Indexes: Epidiomological; Nuclear Fission Safety (NFS); carcinogeni;
non-carcinogenic; Mayak; Techa River; Semipalatinsk Test Site
General Information: The overall objective of the proposal is to study
the carcinogenic and non-carcinogenic effects of protracted low dose ionizing
radiation. The cohort under study are individuals that lived in the vicinity
of the Mayak facility, Techa River and Semipalatinsk Test Site.
Through workshops, courses, scholarships, ... a climate for closer collaboration
will be established. The collaborators in the NIS institutions will be given
the opportunity to attend meetings, to study and to work in the western
institutions during the project.
The studied cohorts are different in many aspects but when it comes to
the structure and methodology for solving the epidemiological problems they
are quite similar. This will give the partners the possibility to collaborate
in the actions planned at increasing research development.
A parallel proposal addressing the Nuclear Fission Safety (NFS) programme
has been submitted by the same researchers. The present proposal is focusing
on the data base improvement e.g. update of the information on death and
birth rates, migration, and if possible identify control groups. The importance
of a thorough epidemiological work-up before any conclusions can be drawn
is going to be emphasized. The NFS proposal focuses on the actual calculations
and analyses of the data.
Achievements: Foreseen Results
The present proposal is aiming at further strengthening of the ongoing
collaborations with the institutions in the former Soviet Union. It will
focus on enhancement of research developments and skills.
Start Date: 1997-05-01
End Date: 1999-10-31
Duration: 30 months
Project Status: Completed
Project Funding: 240000.00 ECU
Programme Type: 4th FWP (Fourth Framework Programme)
Programme Acronym : INCO
Subprogramme Area: Health - Health consequences of radiation exposure
Project Reference: IC15960312
Contract Type: CSC (Cost-sharing contracts)
Prime Contractor
Organisation: Karolinska Institute
Organisation Type: Education
Department: Department of General Oncology Radiumhemmet
Address: PO Box 100
Postcode: 171 76
City: Stockholm
Region: STOCKHOLM
Country: SWEDEN
Contact Person: Name: HALL, Per
Tel: +46-87-294314
Fax: +46-83-124458
Email: pha@rah.ks.se
Other Contractors
Organisation Name: BUNDESAMT FUER STRAHLENSCHUTZ
Organisation Type: Research
Contact Person: SURKART, Werner
Department: INSTITUT FUER STRAHLENHYGIENE
Address: 1 Ingolstädter Landstraße 1
City: OBERSCHLEISSHEIM
Region: BAYERN
OBERBAYERN
München, Landkreis
Org. Country: GERMANY
Postcode: 85764
Telephone: +49-893-1603200
Fax: +49-893-1603202
E-mail: burkart@bfs.de
Organisation Name: URALS RESEARCH CENTRE FOR RADIATION MEDICINE
Organisation Type: Research
Contact Person: AKLEYEV, Alexander V.
Address: Medgorodok
City: CHELYABINSK
Org. Country: RUSSIAN FEDERATION
Postcode: 454076
Telephone: +7-351-2344331
Fax: +7-351-2344321
E-mail: akleye@urcrm.chel.su
Organisation Name: INSTITUTE OF REGIONAL MEDICO-ECOLOGICAL PROBLEMS
Organisation Type: Research
Contact Person: SHOIKET, Jakov
Address: 126 Papanintsev Street 126
PO Box 4663
City: BARNAUL
Org. Country: RUSSIAN FEDERATION
Postcode: 656043
Telephone: +7-385-2239212
Fax: +7-385-2239212
E-mail: eev@biomed.altai.su
Organisation Name: Institute of Biophysics - Branch 1
Organisation Type: Research
Contact Person: LYUBCHANSKY, E.R
Department: Branch nr. 1
Address: 19 Ozeskoe Shosse
City: Ozyorsk
Org. Country: RUSSIAN FEDERATION
Postcode: 456780
Telephone: +7-351-7175464
Fax: +7-351-7122374
E-mail: elyubch@fiblgnc.chel-65.chel.su
Organisation Name: LUDWIG-MAXIMILIANS UNIVERSITY OF MUNICH
Organisation Type: Education
Contact Person: KELLERER, Albrecht (Professor Dr)
Department: STRAHLENBIOLOGISCHES INSTITUT
Address: Schillerstrasse 42
City: MUENCHEN
Region: BAYERN
OBERBAYERN
München, Kreisfreie Stadt
Org. Country: GERMANY
Postcode: 80336
Telephone: +49-895-996818
Fax: +49-895-996840
E-mail: AMK.SBI@LRZ.UNI-Muenchen.DE
Record Control Number: 52563
Quality Validation Date: 2001-02-23
Update Date: 2003-03-05
Project Acronym: ERA-DATABASE
Title: Update and further development of the european radiobiology archives
Subject Index : Nuclear Fission; Medicine, Health; Radiation Protection;
Safety; Scientific Research
Objective: The International Radiobiology Archives is a cooperative venture
by European,jointly with Russian, US, and Japanese scientists to collect
and safeguard data from long-term radiation studies on animals to make them
available for furthe revaluation. The proposed work will complete and extend
the present database and publish it on CD Rom with explanations for distribution
to scientists and their institutions. It will also develop a Website containing
information on such studies. The database will enable scientists to improve
with modern methods organspecific dosimetric models for incorporated radionuclides,
and to assess risk estimates especially for radionuclides for which no human
data are available. In addition, the database will be useful for studies
on aging, risks of cancer, andto test theories on synergistic effects.
Start Date: 2000-01-09
End Date: 2003-08-31
Duration: 44 months
Project Status: Execution
Project Cost: 191104.00 euro
Project Funding: 191100.00 euro
Programme Type: EAEC FWP (Euratom Framework Programme)
Programme Acronym : FP5-EAECTP C
Subprogramme Area: Support for research infrastructures - Radiation protection
and health
Project Reference: FIGH-CT-2000-20097
Contract Type: CSC (Cost-sharing contracts)
Prime Contractor
Organisation: GSF-RESEARCH CENTER FOR ENVIRONMENT AND HEALTH
Organisation Type: Research
Department: INSTITUT FUER STRAHLENBIOLOGIE
Address: Ingolstädter Landstrasse 1
Postcode: 85764
City: Neuherberg
Region: BAYERN
OBERBAYERN
Dachau
Country: GERMANY
Contact Person: Name: KINDER, Juergen (Dr)
Tel: +49-893-1872213
Fax: +49-893-1873372
Email: ertel@gsf.de
Other Contractors
Organisation Name: National Radiological Protection Board
Organisation Type: Research
Contact Person: TALBOT, David (Dr)
City: Didcot - Chilton
Region: SOUTH EAST (UK)
BERKSHIRE, BUCKINGHAMSHIRE, OXFORDSHIRE
Oxfordshire
Org. Country: UNITED KINGDOM
Postcode: OX11 0RQ
Telephone: +44-123-5822633
Fax: +44-123-5833891
E-mail: david.talbot@nrpb.org.uk
Organisation Name: COMMISSARIAT A L'ENERGIE ATOMIQUE
Organisation Type: Non Commercial
Contact Person: DUTRILLAUX, Bernard (Dr)
Department: EXPERIMENTAL CANCEROLOGY LABORATORY
DEPARTMENT OF RADIOBIOLOGY AND RADIOPATHOLOGY - LIFE SCIENCE DIVISION
Address: Avenue du General Leclerc 60-68
BP 6
City: FONTENAY AUX ROSES
Region: ÎLE DE FRANCE
Hauts-de-Seine
Org. Country: FRANCE
Postcode: 92265
Telephone: +33-1-46548585
Fax: +33-1-46549180
E-mail: bernard.dutrillauxacurie.fr
Organisation Name: EUROPEAN LATE EFFECTS PROJECT GROUP
Organisation Type: Research
Contact Person: HOPEWELL, John D. (Professor)
Department: ANATOMIE ET CYTOLOGIE PATHOLOGIQUES
Address: CHU Sart Tilman
City: LIEGE
Region: RÉGION WALLONNE
LIÈGE
Liège (Arrondissement)
Org. Country: BELGIUM
Postcode: 4000
Telephone: +44-1865-225848
Fax: +44-1865-225847
E-mail: john.hopewell@resin.ox.ac.uk
Organisation Name: ITALIAN AGENCY FOR NEW TECHNOLOGY, ENERGY AND THE ENVIRONMENT
Organisation Type: Research
Contact Person: COVELLI, Vincenzo (Dr)
Department: DIVISONE PROTEZIONE DELL'UOMO E DEGLI ECOSISTEMI
Address: Via Anguillarese 301
CP 2358
City: CAPENA
Region: LAZIO
Roma
Org. Country: ITALY
Postcode: 00060
Telephone: +39-0630-483401
Fax: +39-0630-484270
E-mail: covelli@casaccia.enea.it
Organisation Name: LUDWIG-MAXIMILIANS UNIVERSITY OF MUNICH
Organisation Type: Education
Contact Person: V. FUCHS, Detlef (Mr)
Department: STRAHLENBIOLOGISCHES INSTITUT
Address: Schillerstrasse 42
City: MUENCHEN
Region: BAYERN
OBERBAYERN
München, Kreisfreie Stadt
Org. Country: GERMANY
Postcode: 80336
Telephone: +49-892-18034/49
Fax: +49-893-38297
Record Control Number: 52733
Quality Validation Date: 2002-09-10
Update Date: 2003-07-18
Project Acronym: LOW DOSE RISK MODELS
Title: Improved cancer risk quantification for environmental, medical and
occupational exposures to low doses of ionising radiation by mechanistic
models
Subject Index : Nuclear Fission; Medicine, Health; Radiation Protection;
Safety
Objective: This project will contribute to the solution of the important
open problem of quantification of stomatic radiation risks to humans at
low doses (below, say, 10 mSv) and low dose rates of ionising radiation
of various qualities at least for the organs lung, thyroid and bone. Since
this problem cannot be solved by basic biological investigations nor by
epidemiological studies alone, the scientific knowledge from both areas
will be combined to develop and test quantitative mechanistic models for
the dose-time-effect surfaces of radiation carcinogenesis in these organs.
Existing data and theories are evaluated and used for the modelling of radiation
transport and interaction, for the modelling of subsequent damage and repair
of DNA, genes, cells and organs taking normal oxidative damage into account,
and for the multi-step modelling of carcinogenesis. Conclusions will be
drawn for the general radiation of the worker and the public.
Start Date: 2000-02-01
End Date: 2003-01-31
Duration: 36 months
Project Status: Completed
Project Cost: 2.50 million euro
Project Funding: 1.10 million euro
Programme Type: EAEC FWP (Euratom Framework Programme)
Programme Acronym : FP5-EAECTP C
Subprogramme Area: Radiation protection and health - Risk estimates for
exposures at low dose and low dose rate
Project Reference: FIGH-CT-1999-00005
Contract Type: CSC (Cost-sharing contracts)
Prime Contractor
Organisation: GSF-RESEARCH CENTER FOR ENVIRONMENT AND HEALTH
Organisation Type: Research
Department: INSTITUT FUER STRAHLENSCHUTZ
Address: Ingolstaedter Landstrasse 1
Postfach 11 29
Postcode: 85764
City: OBERSCHLEISSHEIM
Region: BAYERN
OBERBAYERN
München, Landkreis
Country: GERMANY
Contact Person: Name: KINDER, Wolf (Dr)
Tel: +49-893-1872213
Fax: +49-893-1873372
Email: ertel@gsf.de
Other Contractors
Organisation Name: THE UNIVERSITY OF MILANO
Organisation Type: Education
Contact Person: MANTEGAZZA, Paolo (Professor)
Department: DIPARTIMENTO DI FISICA
Address: Via Celoria 16
City: Milano
Region: LOMBARDIA
Org. Country: ITALY
Postcode: 20133
Telephone: +39-022-392655
Fax: +39-022-392630/208
E-mail: andrea.ottolenghi@mi.infn.it
Organisation Name: ASSOCIATION POUR LE DEVELOPPEMENT DE LA PHYSIQUE ATOMIQUE
Organisation Type: Research
Contact Person: BONNET, Jacques (Dr)
Department: CENTRE DE PHYSIQUE DES PLASMAS ET DE LEURS APPLICATIONS DE
TOULOUSE
Address: 118 Route de Narbonne 118
City: TOULOUSE
Region: SUD-OUEST
MIDI-PYRÉNÉES
Haute-Garonne
Org. Country: FRANCE
Postcode: 31062
Telephone: +33-56-1556859
Fax: +33-56-1556332
E-mail: adpa@cpat.ups-tlse.fr
Organisation Name: UNIVERSITY OF SALZBURG
Organisation Type: Education
Contact Person: HOFMANN, Werner (Professor)
Department: INSTITUTE OF PHYSICS AND BIOPHYSICS - FACULTY OF NATURAL SCIENCES
Address: Hellbrunnerstrasse 34
City: SALZBURG
Region: WESTÖSTERREICH
SALZBURG
Salzburg und Umgebung
Org. Country: AUSTRIA
Postcode: 5020
Telephone: +43-662-8044570/5
Fax: +43-662-8044150
E-mail: werner.hofmann@sgb.ac.at
Organisation Name: NATIONAL RADIOLOGICAL PROTECTION BOARD
Organisation Type: Research
Contact Person: WELLBURN, Janet (Mrs)
Department: RADIATION EFFECTS
City: DIDCOT,HARWELL,CHILTON
Region: SOUTH EAST (UK)
BERKSHIRE, BUCKINGHAMSHIRE, OXFORDSHIRE
Oxfordshire
Org. Country: UNITED KINGDOM
Postcode: OX11 0RQ
Telephone: +44-1235-822719
Fax: +44-1235-833891
E-mail: janet.wellburn@nrpb.org.uk
Organisation Name: MEDICAL RESEARCH COUNCIL
Organisation Type: Research
Contact Person: MCLAREN, Diane (Dr)
Department: RADIATION AND GENOME STABILITY UNIT
Address: Harwell
City: Didcot
Region: SOUTH EAST (UK)
BERKSHIRE, BUCKINGHAMSHIRE, OXFORDSHIRE
Oxfordshire
Org. Country: UNITED KINGDOM
Postcode: OX11 0RD
Telephone: +44-1865-222580
Fax: +44-1865-222549
E-mail: diane.mclaren@headoffice.mrc.ac.uk
Organisation Name: NATIONAL INSTITUTE OF PUBLIC HEALTH AND ENVIRONMENT
Organisation Type: Research
Contact Person: ELZINGA, Gijs (Dr)
Department: LABORATORY OF RADIATION RESEARCH
Address: Anthonie van Leuwenhoeklaan 9
PO Box 1
City: BILTHOVEN
Region: WEST-NEDERLAND
UTRECHT
Org. Country: NETHERLANDS
Postcode: 3720 BA
Telephone: +31-30-2742345
Fax: +31-30-2744411
E-mail: gijs.elzinga@rivm.nl
Organisation Name: GERMAN CANCER RESEARCH CENTER
Organisation Type: Research
Contact Person: ZUR HAUSEN, Harald / Josef (Professor)
Department: ZENTRALE EINHEIT BIOSTATISTIK
Address: Im Neuenheimer Feld 280
City: Heidelberg
Region: BADEN-WÜRTTEMBERG
KARLSRUHE
Heidelberg, Stadtkreis
Org. Country: GERMANY
Postcode: 69120
Telephone: +49-622-1422700
Fax: +49-622-1422708
E-mail: e.egenlauf@dkfz-heidelberg.de
Organisation Name: PAUL SCHERRER INSTITUT
Organisation Type: Research
Contact Person: WINKLER, Fritz (Professor)
Department: LIFE SCIENCE DEPARTMENT
City: VILLIGEN
Region: SCHWEIZ/SUISSE/SVIZZERA
Org. Country: SWITZERLAND
Postcode: 5232
Telephone: +41-56-3102043
Fax: +41-56-3102849
Record Control Number: 52739
Quality Validation Date: 2003-04-01
Update Date: 2003-12-04
Project Acronym: UMINERS + ANIMAL DAT
Title: Quantification of lung cancer risk after low radon exposure and
low exposure rate: synthesis from epidemiologic and experimental data
Subject Index : Nuclear Fission; Medicine, Health; Radiation Protection;
Safety
Objective: Occupational exposure to radon in European uranium mines during
the last 30 years was at low annual rate; follow-up of 10 000 miners over
more than 20 years made it possible to organise a joint analysis. This joint
study has a good statistical power, able to detect lom lung cancer risks
linked to low annual exposure; modifying factors like attained age, dose-rate,
and concomitant exposures (gamma, ore dust) will be studied in this large
cohort. Nested case-control studies will be implemented in order to test
the radon-tobacco interaction. Domestic radon plus occupational exposure
will be studied in one of the case-control studies. Animal experiments will
be continued. Mechanistic modelling will be applied to both animal and human
data.
Start Date: 2000-02-01
End Date: 2003-08-01
Duration: 42 months
Project Status: Execution
Project Cost: 1.54 million euro
Project Funding: 795332.00 euro
Programme Type: EAEC FWP (Euratom Framework Programme)
Programme Acronym : FP5-EAECTP C
Subprogramme Area: Radiation protection and health - Risk estimates for
exposures at low dose and low dose rate
Project Reference: FIGH-CT-1999-00013
Contract Type: CSC (Cost-sharing contracts)
Prime Contractor
Organisation: INSTITUT DE RADIOPROTECTION ET DE SURETE NUCLEAIRE
Organisation Type: Research
Department: DÉPARTEMENT DE PROTECTION DE LA SANTÉ DE L'HOMME
ET DE DOSIMÉTRIE
Address: Rue Auguste Lemaire
Postcode: 92262
City: FONTENAY AUX ROSES
Region: ÎLE DE FRANCE
Hauts-de-Seine
Country: FRANCE
Contact Person: Name: LIVOLANT, Michel (Dr)
Tel: +33-1-46548267
Fax: +33-1-46549511
Email: michel.livolant@ipsn.fr
Other Contractors
Organisation Name: GSF-RESEARCH CENTER FOR ENVIRONMENT AND HEALTH
Organisation Type: Research
Contact Person: KINDER, Juergen (Dr)
Department: INSTITUT FUER STRAHLENSCHUTZ
Address: Ingolstaedter Landstrasse 1
Postfach 11 29
City: OBERSCHLEISSHEIM
Region: BAYERN
OBERBAYERN
München, Landkreis
Org. Country: GERMANY
Postcode: 85764
E-mail: ertel@gsf.de
Organisation Name: BUNDESAMT FUER STRAHLENSCHUTZ
Organisation Type: Research
Contact Person: OBERLÄNDER, Henrich (Mr)
Department: INSTITUT FUER STRAHLENHYGIENE
Address: 1 Ingolstädter Landstraße 1
City: OBERSCHLEISSHEIM
Region: BAYERN
OBERBAYERN
München, Landkreis
Org. Country: GERMANY
Postcode: 85764
Telephone: +49-534-1885240
Fax: +49-534-1885255
E-mail: hoberlaender@bfs.de
Organisation Name: National Radiological Protection Board (NRPB)
Organisation Type: Research
Contact Person: WELLBURN, Janet (Mrs)
Department: Population Exposure Department
Address: Chilton
City: Didcot
Region: SOUTH EAST (UK)
BERKSHIRE, BUCKINGHAMSHIRE, OXFORDSHIRE
Oxfordshire
Org. Country: UNITED KINGDOM
Postcode: OX11 0RQ
Telephone: +44-1235-822719
Fax: +44-1235-833891
E-mail: janet.wellburn@nrpb.org.uk
Organisation Name: COMMISSARIAT A L'ENERGIE ATOMIQUE
Organisation Type: Research
Contact Person: DUTRILLAUX, Bernard (Dr)
Department: DEPARTMENT OF RADIOBIOLOGY AND RADIOPATHOLOGY - LIFE SCIENCE
DIVISION
Address: Avenue du General Leclerc 60-68
BP 510
City: FONTENAY AUX ROSES
Region: ÎLE DE FRANCE
Hauts-de-Seine
Org. Country: FRANCE
Postcode: 92265
Telephone: +33-14-6548585
Fax: +33-14-6549180
E-mail: bernard.dutrillauxacurie.fr
Organisation Name: AEA TECHNOLOGY PLC
Organisation Type: Other
Contact Person: ROE, Simon (Dr)
Department: BIOSCIENCES DEPARTMENT
Address: Harwell 551
City: DIDCOT,HARWELL,CHILTON
Region: SOUTH EAST (UK)
BERKSHIRE, BUCKINGHAMSHIRE, OXFORDSHIRE
Oxfordshire
Org. Country: UNITED KINGDOM
Postcode: OX11 0RA
Telephone: +44-1235-435558
Fax: +44-1235-432997
E-mail: simon.roe@aeat.co.uk
Organisation Name: NATIONAL INSTITUTE OF PUBLIC HEALTH AND ENVIRONMENT
Organisation Type: Research
Contact Person: ELZINGA, Gijs (Dr)
Department: LABORATORY OF RADIATION RESEARCH
Address: Anthonie van Leuwenhoeklaan 9
PO Box 1
City: BILTHOVEN
Region: WEST-NEDERLAND
UTRECHT
Org. Country: NETHERLANDS
Postcode: 3720 BA
Telephone: +31-30-2742345
Fax: +31-30-2744411
E-mail: gijs.elzinga@rivm.nl
Organisation Name: NATIONAL RADIATION PROTECTION INSTITUTE
Contact Person: FILGAS, Radim
Department: DEPARTMENT OF EXPOSURE CONTROL
Address: Srobarova 48
City: PRAHA 10
Region: CESKA REPUBLIKA
Org. Country: CZECH REPUBLIC
Postcode: 100 00
Telephone: +42-02-67311239
Fax: +42-02-6311410
Record Control Number: 53169
Quality Validation Date: 2003-04-24
Update Date: 2003-05-13
Project Acronym: ERA-DATABASE
Title: Update and further development of the European radiobiology archives
('era-database')
Subject Index : Nuclear Fission; Medicine, Health; Radiation Protection;
Safety; Scientific Research
Objective: The International Radiobiology Archives is a cooperative venture
by European, jointly with Russian, US, and Japanese scientists to collect
and safeguard data from long-term radiation studies on animals to make them
available for further evaluation. The proposed work will complete and extend
the present database and publish it on CD Rom with explanations for distribution
to scientists and their institutions. It will also develop a Website containing
information on such studies. The database will enable scientists to improve
with modern methods organ specific dosimetric models for incorporated radionuclides,
and to assess risk estimates especially for radionuclides for which no human
data are available. In addition, the database will be useful for studies
on aging, risks of cancer, and to test theories on synergistic effects.
Start Date: 2000-09-01
End Date: 2003-12-31
Duration: 40 months
Project Status: Execution
Project Cost: 191100.00 euro
Project Funding: 191100.00 euro
Programme Type: EAEC FWP (Euratom Framework Programme)
Programme Acronym : FP5-EAECTP C
Subprogramme Area: Support for research infrastructures - Radiation protection
and health
Project Reference: FIR1-CT-2000-20097
Contract Type: THN (Thematic network contracts)
Prime Contractor
Organisation: GSF-RESEARCH CENTER FOR ENVIRONMENT AND HEALTH
Organisation Type: Research
Department: INSTITUT FUER STRAHLENBIOLOGIE
Address: Ingolstädter Landstrasse 1
Postcode: 85764
City: Neuherberg
Region: BAYERN
OBERBAYERN
Dachau
Country: GERMANY
Contact Person: Name: KINDER, Juergen (Dr)
Tel: +49-893-1872213
Fax: +49-893-1873372
Email: ertel@gsf.de
Other Contractors
Organisation Name: NATIONAL RADIOLOGICAL PROTECTION BOARD
Organisation Type: Research
Contact Person: TALBOT, David (Mr)
City: DIDCOT, HARWELL, CHILTON
Region: SOUTH EAST (UK)
BERKSHIRE, BUCKINGHAMSHIRE, OXFORDSHIRE
Oxfordshire
Org. Country: UNITED KINGDOM
Postcode: OX11 0RQ
Telephone: +44-1235-822633
Fax: +44-123-5833891
E-mail: david.talbot@nrpb.org.uk
Organisation Name: COMMISSARIAT A L'ENERGIE ATOMIQUE
Organisation Type: Non Commercial
Contact Person: DUTRILLAUX, Bernard (Dr)
Department: EXPERIMENTAL CANCEROLOGY LABORATORY
DEPARTMENT OF RADIOBIOLOGY AND RADIOPATHOLOGY - LIFE SCIENCE DIVISION
Address: Avenue du General Leclerc 60-68
BP 6
City: FONTENAY AUX ROSES
Region: ÎLE DE FRANCE
Hauts-de-Seine
Org. Country: FRANCE
Postcode: 92265
Telephone: +33-14-6548585
Fax: +33-14-6549180
E-mail: bernard.dutrillauxacurie.fr
Organisation Name: EUROPEAN LATE EFFECTS PROJECT GROUP
Organisation Type: Research
Contact Person: HOPEWELL, John D. (Professor)
Department: ANATOMIE ET CYTOLOGIE PATHOLOGIQUES
Address: CHU Sart Tilman
City: LIEGE
Region: RÉGION WALLONNE
LIÈGE
Liège (Arrondissement)
Org. Country: BELGIUM
Postcode: 4000
Telephone: +44-1865-225848
Fax: +44-186-5225847
E-mail: john.hopewell@resin.ox.ac.uk
Organisation Name: ITALIAN AGENCY FOR NEW TECHNOLOGY, ENERGY AND THE ENVIRONMENT
Organisation Type: Research
Contact Person: COVELLI, Vincenzo (Dr)
Department: DIVISONE PROTEZIONE DELL'UOMO E DEGLI ECOSISTEMI
Address: Via Anguillarese 301
CP 2358
City: CAPENA
Region: LAZIO
Roma
Org. Country: ITALY
Postcode: 00060
Telephone: +39-063-0483401
Fax: +39-06-30484270
E-mail: covelli@casaccia.enea.it
Organisation Name: LUDWIG-MAXIMILIANS UNIVERSITY OF MUNICH
Organisation Type: Education
Contact Person: V. FUCHS, Detlef (Mr)
Department: STRAHLENBIOLOGISCHES INSTITUT
Address: Schillerstrasse 42
City: MUENCHEN
Region: BAYERN
OBERBAYERN
München, Kreisfreie Stadt
Org. Country: GERMANY
Postcode: 80336
Telephone: +49-892-1803449
Fax: +49-893-38297
Record Control Number: 59886
Quality Validation Date: 2003-04-01
Update Date: 2003-05-05
Project Acronym: RADCANCERANALYSIS
Title: Radiation cancer analysis and low dose risk estimation: new developments
and perspectives
Subject Index : Economic Aspects; Environmental Protection; Nuclear Fission;
Radiation Protection; Safety
Objective: The objective of the project is networking and research communication.
The aim of the Radiation Cancer Analysis meeting is to provide a international
forum where radiation biologists, epidemiologists and modellers can meet
each other, exchange recent results in their fields of interest and discuss
the implication of their results for the estimates of radiation risks at
low doses. The scientific aim is improving the understanding of the dose-effect
relationship at low doses, discussing the currently used and new methods
to analyse epidemiological data, and comparing the results using different
methods. Current EU contractors in the fields of interest are especially
invited to participate in this meeting, particularly from contracts FIGH-CT1999-00005
(LOW DOSE RISK MODELS), FIGH-CT1999-00013 (UMINERS + ANIMAL DATA) and FIGD-2000-00079
(NDISC). The discussion will focus on the practical implications of the
research for health effects in man arising from enhanced radiation levels,
which may be encountered in the environment, occupationally or as a consequence
of medical radiological applications.
The potential risks of exposure to ionising radiation have been well recognised
for many years. Yet, many uncertainties still exist when it comes to the
estimation of the radiation risks in situations encountered in practical
radiation protection circumstances. These problems have to betackled by a
synthesis of approaches from different disciplines, by combining new insights
in radiation mechanisms, carcinogenesis modelling and epidemiology.
An international scientific meeting is therefore proposed to discuss the
use of mechanistic cancer modelling for the analysis of epidemiological
data and its implications for low dose radiation risks Current EU contractors
in the fields of interest are especially invited to participate in this meeting,
but specialists from outside the EU are requested to present their results
as well The meeting is aimed to provide a forum where radiation biologists,
epidemiologists and modellers can meet each other, exchange recent results
in their fields of interest and discuss the implication of their results
for the estimates of radiation risks at low doses. The proceedings of the
meeting will be published.
Start Date: 2001-12-01
End Date: 2003-01-31
Duration: 14 months
Project Status: Completed
Project Cost: 73201.00 euro
Project Funding: 38994.00 euro
Programme Type: EAEC FWP (Euratom Framework Programme)
Programme Acronym : FP5-EAECTP C
Subprogramme Area: ACCOMPANYING MEASURES
Project Reference: FIGH-CT-2001-06006
Contract Type: ACM (Preparatory, accompanying and support measures)
Prime Contractor
Organisation: NATIONAL INSTITUTE OF PUBLIC HEALTH AND ENVIRONMENT
Organisation Type: Research
Department: LABORATORY OF RADIATION RESEARCH
Address: Anthonie van Leuwenhoeklaan 9
PO Box 1
Postcode: 3720 BA
City: BILTHOVEN
Region: WEST-NEDERLAND
UTRECHT
Country: NETHERLANDS
Contact Person: Name: LEENHOUTS, Henk
Record Control Number: 64042
Quality Validation Date: 2003-04-01
Update Date: 2003-04-15
Project Acronym: HELMUT SCHÖLLNBERGER
Title: Risk estimation for ionizing radiation using mechanistic cancer
modelling
Subject Index : Nuclear Fission; Measurement Methods; Medicine, Health;
Radiation Protection; Radioactive Waste
Objective: The main objective is risk analysis for low doses of ionising
radiation using a biologically based cancer model. Important aspects are:
the form of the dose-effect relationship at very low doses and the question
whether it is linear, linear-quadratic or whether there is a threshold.
The ultimate aim is the derivation of improved estimates of radiation risks
for radiological protection.
The main task for the applicant will be to continue working with the two-mutation
carcinogenesis (TMC) model, to advance the model and make it applicable
for other data sets and cancer in other organs, to use suitable animal data
to investigate mechanistic aspects of radiological effects and to investigate
suitable epidemiological data for description and model testing.
The proposed research allows to consider and possibly implement new concepts
such as an induction of cellular defence mechanisms and bystander effects.
These important radiobiological phenomena could be included and tested within
the framework of the TMC model.
The applicant works in the field of low dose research since more than 8
years and is currently involved with the EU project CEC .Contract FIGH-CT-1999-00005.
His range of knowledge and expertise in the field of the proposed research
is interesting to be incorporated into the TMC model.
Start Date: 2002-09-01
End Date: 2004-08-31
Duration: 24 months
Project Status: Execution
Project Cost: 133350.00 euro
Project Funding: 133350.00 euro
Programme Type: EAEC FWP (Euratom Framework Programme)
Programme Acronym : FP5-EAECTP C
Subprogramme Area: RTD activities of a generic nature
Project Reference: FIGH-CT-2002-50513
Contract Type: RGI (Research grants (individual fellowships))
Prime Contractor
Organisation: NATIONAL INSTITUTE OF PUBLIC HEALTH AND ENVIRONMENT
Organisation Type: Research
Department: LABORATORY OF RADIATION RESEARCH
Address: 9 Antonie van Leeuwenhoeklaan 9
PO Box 1
Postcode: 3720 BA
City: BILTHOVEN
Region: WEST-NEDERLAND
UTRECHT
Country: NETHERLANDS
Contact Person: Name: BRUGMANS, Marco (Dr)
Record Control Number: 199321076
Quality Validation Date: 1994-12-02
Update Date: 1995-08-25
Title in English: Projection of radiation-induced cancer risks across time
and populations
Author(s): MUIRHEAD C R
National Radiological Protection Board, Chilton, Didcot (GB)
Bibliographic Reference: Extract: Statistics of human exposure to ionising
radiation : Proceedings of a Workshop held in Oxford (GB), April 2-4, 1990
(1991) pp. 321-325 EUR 13781; ISBN 1 870965 08 6; Nuclear Technology Publishing,
P.O. Box No. 7, Ashford, Kent TN23 1YW
Facet Codes: Health physics, radiation protection, radioactive contamination
of the environment
Availability in Languages: en
Publication Year: 1991
Publication Type: An extract from conference proceedings or from reports
Subject Index : Medicine, Health; Radiation Protection; Mathematics, Statistics
Record Control Number: 126104324
Quality Validation Date: 1991-01-25
Update Date: 1994-12-23
Title in English: METHOD FOR CALCULATING TIME DEPENDENT INDIVIDUAL AND
COLLECTIVE CANCER RISKS IN THE ACCIDENT CONSEQUENCE ASSESSMENT CODE UFOMOD
Author(s): STEINHAUER C;MATZERATH C
Bibliographic Reference: NUCLEAR SCIENCE AND TECHNOLOGY. JOINT CEC/OECD(NEA)
WORKSHOP ON RECENT ADVANCES IN REACTOR ACCIDENT CONSEQUENCE ASSESSMENT HELD
IN ROME (IT), 25-29, JAN., 1988, PUBL. 1988, BY: OFFICE FOR OFFICIAL PUBLICATIONS
OF THE EUROPEAN COMMUNITIES, L-2985 LUXEMBOURG (LU), (EUR 11408 EN), PP.
278-288
Availability in Languages: en
Publication Year: 1988
Publication Type: An extract from conference proceedings or from reports
Euroabstracts Number: EAB126104324
Subject Index : Nuclear Fission
Record Control Number: 24871
Quality Validation Date: 2000-06-30
Update Date: 2003-08-07
Abstract: This research project deals with the distribution of radon concentration
in the environment and its health consequences for young people. Epidemiological
correlations will also be investigated in addition to particularly severe
conditions of chemical and radioactive pollution. Preliminary studies in
the region of Kuzbas (Siberia) showed that the concentration of radon both
in coal mines and in housing near the mines is 3 to 15 times higher than
the level recommended by the European Community. The prevalence of cancer
among children (leucosis) is higher in these areas than in others. The effect
of high radon concentrations will be analyzed and different investigations
will be conducted on the health of the population affected by the activities
of mining (Russia and Ukraine), a uranium plant (Kazakhstan), curie-therapy
treatment in a hospital (Kazakhstan), and of specific situations such as
the Chernobyl disaster, nuclear-weapons testing sites and radioactive waste
storage. The main goal of this project is to assist the participants from
the NIS in the collection of pollution data (radon, gamma and chemical data)
and to analyze their effects on the population. It is also planned to set
up a data bank of the radioactive and chemical situation in different regions
of Russia, Ukraine and Kazakhstan. This project will define the risk of manifestation
of oncological diseases as a function of radon concentration. One participant
will define a mathematical model, built on the collected data of this project,
which will evaluate the risk of radon as a function of the chemical, radioactive
and radon levels at one site. The results will therefore lead to the creation
of methods for preventing health risks for the population. Other expected
results are: the validation of Russian measurement techniques for radon
concentration; the creation of a databank consisting of parameters of specific
sites such as coal mines, uranium plants, hospital, and such as radon concentration,
environmental radioactivity level (gamma measurements) and chemical and
sanitary pollution levels (e.g. number of pulmonary sicknesses, leukaemia).
The data bank will lead to a mathematical analysis model which will correlate
the radon concentration and the health risk probability for the population,
notably the youngest part.
Innovative Aspects: The study resulted in 100 measurements of indoor radon
of residential premises in some villages of Pereyaslav-Chmelnitski andBoguslav
district in Kiev region. The results have been obtained by the method of
passive track dosimetry with an exposure time of about 1-2 months.
The results showed that an average value of the indoor 222Rn equilibrium
equivalent concentration (EEC) for Boguslav at 107 Bqm-3 (EECmax = 374 Bqm-3),
for Pereyaslav-Chmelnitski district - 34 Bqm-3 (EECmax = 65 Bqm-3) giving
a 3-fold differences for districts. The analysis of the parameters of frequency
distribution for Boguslavs buildings shows that a probability of finding
buildings with the concentration above 200 Bqm-3 is about 0.8%.
The average values of weighted 222Rn effective doses are found 6.8 mSv/year
for Boguslav district, 2.1 mSv/year for Pereyaslav-Chemnitsi district. However,
in some cases, the individual effective doses may constitute more than 50
mSv/year which may conduct to oncological incidences.
Subject Descriptors: Radioactivity
Subject Index : Radiation Protection
Collaboration Sought: Information exchange/Training
Contact Details
Contact Name: CHAMBAUDET, A.
Department: Laboratoire de Microanalyses Nucléaires
Contact Organisation: Université de Franche-Comté
City: Besançon
Country: FRANCE
Telephone Number: +33-381666500
Fax Number: +33-381666522
Related Programme(s) / Project(s)
Programme Project Reference Project Title
INTAS INTAS-93-3001 Radioactive environmental investigations (radon 222
and gamma pollution) and epidemiological studies of effect in young people
Radiation protection
(50M €)
Topics for the Call 2004
Quantification of risks associated with
low and protracted exposure
(1) Epidemiological studies of exposed populations in the Southern Urals
(Integrated Project, RAD PROT-2004-3.3.1.1-1)
Objective: To better quantify the risks of radiation from epidemiological
studies of exposed cohorts in the Southern Urals.
Scope:
Improvement and validation of the dosimetry
system
for the Techa River cohort
Improvement and validation of the dosimetry system for the Mayak workforce
Epidemiological studies of the Techa River offspring cohort addressing all
potential health effects (cancer - mortality and morbidity, non-cancer, developmental
and hereditary effects, etc)
Epidemilogical studies of non-cancer late health effects in the Mayak workforce
A fully integrated, multi-disciplinary project that secures the active participation
of epidemiologists, dosimetrists, plant operators, operational health physicists,
etc, will be required to achieve the objectives. The project should be conceived
within a longer term perspective (ie, beyond the project duration) that may
be required to extract full value from studies of these cohorts. The research
must be fully co-ordinated and avoid duplication with related research being
carried out by others, in particular the RF and US.
(2) Epidemiological studies of exposed populations (excluding the Southern
Urals) (Specific Targeted Research Project(s), RAD PROT-2004-3.3.1.1-2)
Objective: To better quantify and understand the risks associated with low
and protracted exposures to ionising radiation of different forms and quality
or to help resolve major public health concerns.
Scope:
Epidemiological studies of exposed populations
that offer the greatest potential to contribute to the better quantification
of risks at low and/or protracted doses
Epidemiological studies of exposed populations that offer the greatest potential
to help resolve major public health concerns
All health effects (cancer mortality and morbidity, non-cancer, developmental
and hereditary effects, etc)
Project(s) will require a multi-disciplinary approach. Studies of more than
one exposed population within a project are to be encouraged, in particular
where this would enable resources to be used more cost effectively and/or
promote the development of more coherent and enhanced methodological approaches.
Medical exposures and natural sources of
radiation
(1) Safety and efficacy of diagnostic imaging techniques other than CT (Co-ordination
Action, RAD PROT-2004-3.3.2.1-1)
Objective: To develop quality criteria and guidelines for new and emerging
diagnostic imaging techniques.
Scope:
Networking of activities in Member and
Associated States
Diagnostic imaging techniques (including nuclear medicine but excluding
CT) associated with high individual doses or which are applied extensively
to more sensitive groups (ie, children)
A Co-ordination Action of limited scale and ambition will be sufficient
to achieve these objectives. The network should be broadly based, including
clinicians, radiologists, radiation protectionists and equipment manufacturers.
Protection of the environment and radioecology
(1) Assessment and management of the impact of radionuclides on man and
the environment (Co-ordination Action(s), RAD PROT-2004-3.3.3.1-1)
Objectives: To maintain and enhance competence in the European Union for
the assessment and management of the impact of natural and artificial sources
of radiation on man and the environment and to make better use of existing
resources.
Scope:
Networking of the major research actors and end users
Evaluate the potential for establishing deeper and sustainable collaboration
and the contribution of networks of excellence in this context
Mechanisms to enable effective absorption or uptake of outcomes by other
research actors and end users
The network or networks should comprise the research community and end users.
Preference will be given to co-ordination actions that are broad ranging (eg,
in terms of the range of nuclides and environments covered) but those more
narrowly based (eg, covering only one sector of the environment) will be
considered on their merits.
Risk and emergency management
(1) Risk Governance (Specific Targeted Research Project(s), RAD PROT-2004-3.3.4.1-1)
Objectives: To demonstrate the efficacy and practicability in the nuclear
sector of new and emerging approaches for risk governance.
Scope:
Demonstration, through prospective case study(ies), of new approaches to
risk governance that have the potential to find broad social and technical
acceptance
Identification of the strengths and weaknesses of these approaches
Guidance on the application of these approaches in the nuclear sector more
generally
Activities should be largely restricted to demonstration of the approaches
as opposed to their further refinement. The active participation of the research
community and end users (industry and/or regulators) will be essential to
meet the objectives.
Protection of the workplace
(1) Protection in the workplace (Co-ordination Action(s), RAD PROT-2004-3.3.5.1-1)
Objectives: To maintain and enhance competence for the monitoring and management
of occupational exposures and to make better use of existing resources within
Europe.
Scope:
Networking of the major research actors and end users
Evaluate the potential for establishing deeper and sustainable collaboration
and the contribution of networks of excellence in this context
Mechanisms to enable effective absorption or uptake of outcomes by other
research actors and end users
The network or networks should comprise the research community and end users.
Preference will be given to co-ordination actions that are broad ranging (eg,
in terms of the range of workplaces covered) but those more narrowly based
(eg, covering only one type of workplace) will also be considered on their
merits.
Radiation protection (50M €)
Indicative topics for future calls
Quantification of risks associated with
low and protracted exposure
Future calls may include further epidemiological studies and molecular and
cellular biology research.
Medical exposures and natural sources of
radiation
Future calls may cover further research on the medical uses of radiation,
in particular, in therapy and networking to better integrate activities within
Member and Associated States concerned with the assessment and management
of exposures from NORM.
Protection of the environment and radioecology
Future calls in this area are not foreseen but the situation will be kept
under review.
Risk and emergency management
Future calls in this area are not foreseen but the situation will be kept
under review.
Protection of the workplace
Future calls in this area are not foreseen but the situation will be kept
under review.
This is a list (1994-2003) of European references on Cancer/Radioactivity
research.
Topics for the Call 2004 on Radioprotection
and indicative topics for future calls
We are interested in any further information, statistical data, methodologies
and contacts.for proposals.
Please visit http://www.cita.es/mcr
and send a message to miguel@cita.es
Ing. Miguel Ángel Gallardo Ortiz,
WWW.CITA.ES
Tel: (+34) 914743809 Fax: 902998379 Móvil (GSM): (+34) 619776475,
Apartado (P.O. Box) 17083, E-28080 Madrid, Spain, E-mail:
miguel@cita.es